CUET CHEMISTRY SYLLABUS


CUET Chemistry 2022 syllabus has been released.

CUET chemistry syllabus is divided into three parts: organic chemistry, physical chemistry, and inorganic chemistry.

Applicants can check the subject-wise detailed CUET chemistry syllabus for 2022 here as well as the official website of IIT JAM.

1. PART-A will consist of 25 objective questions (MCQs) and will include English, GeneralAwareness, Mathematical Aptitude and Analytical Skills.

2. PART-B will consist of 75 objective questions (MCQs) from the following syllabus:

CUET CHEMISTRY

SR. No Inorganic Chemistry
1 Atomic Structure: Evidence for the electrical nature of matter; discharge tube experiments,thomson atomic model;Rutherford model; Bohr's model of hydrogen atom; probability picture of electron; quantum numbers;Shapes of s, p, d, orbits; Aufbau's and pauli's exclusion principles, Hand's Rule of maximum multiplicity;Electronic configurations of the elements; effective nuclear charge.
2 Chemical Bonding: Covalent bond Valence Bond Theory (VBT) and its limitations, directional characteristics of covalentbond, various types of hybridization and shapes of simple inorganic molecules and ions. Valence ShellElectron Pair Repulsion Theory (VSEPR Theory) to NH3, H3O + , SF4, ClF3, ICl2 - and H2O. MolecularOrbital Theory, homonuclear and heteronuclear diatomic molecules(CO and NO), multicenter bonding inelectron deficient molecules, bond strength and bond energy, percentage ionic character from dipolemoment and electronegativity difference.
3 Periodic Properties: Atomic and ionic radii, ionization energy, electron affinity and electronegativity, definition, methods ofdetermination or evaluation, trends in periodic table and applications in predicting and explaining thechemical behaviour.
4 Acids, Bases and Non Aqueous Solvents: Arrhenius Concept and Bronsted Theory. The Lux Flood Solvent Systems. Lewis Concept of Acids andBases.Physical Properties of a solvent. Types of Solvents and their general Characteristics. Reactions innon aqueous solvents with respect to liquid NH3 and liquid SO2.
5 s block elements: Comparative study including diagonal relationship of groups, salient features of Hydrides, solvation andcomplexation tendencies including their function in biosystems. An introduction to alkyls and aryls.
6 P block elements A : Comparative study including diagonal relationship of groups 13 and 14. Group 13-Hydrides of Boron,diborane, and higher boranes, borazine, borohydrides. Group 14-Fullerenes, carbides, fluorocarbons,silicates (structural principle).
7 P block elements B : Comparative study including diagonal relationship of groups 15, 16 and 17. group 15- phosphazenes,group 16 tetra sulfur tetranitride, group 17 basic properties of halogens, interhalogens and polyhalides.
8 Chemistry of noble gases: Chemical properties of Noble Gases, Chemistry of Xenon, structure and bonding in Xenon compounds.
9 Chemistry of the Elements of the First Transition Series: Characteristic properties of the d-Block elements. Properties of the elements of the first transition series,their binary compounds, and complexes illustrating relative stability of their oxidation states, coordination number and geometry.
10 Coordination compounds: werner's Co-ordination theory and its experimental verification, effective atomic number concept,chelates, nomenclature of co-ordination compounds. Isomerism in co-ordination compounds, valencebond theory of transition metal complexes
11 Oxidation and Reduction: Use of redox potential data-analysis of redox cycle, redox stability in water frost, Latimer and pourbaixdiagrams. Principles involved in the extraction of the elements.
12 Chemistry of the Lanthanide Elements: Electronic structure, oxidation states and ionic radii and lanthanide contraction, complex formation,occurrence and isolation, lanthanide compounds.
13 Chemistry of the elements of the second and third transition series: General characteristics, comparative treatment with their 3d analogues in respect of Ionic radii, oxidationstates, magnetic behaviour, spectral properties and stereochemistry.
14 Chemistry of Actinides: General features and chemistry of actinides, chemistry of separation of Np, Pu and Am from U,similarities between later actinides and later lanthanides.
15 Ionic Solids: Ionic structures, radius ratio effect and coordination number, limitation of radius ratio rule, lattice defects,semiconductors, lattice energy and Born-Haber cycle, salvation energy and solubility of ionic solids,Polarizing power and polarizability of ions,Fajan's Rule and Metalic Bond - free electron, valence bond andband theories.
16 Metal-Ligand Bonding in Transition Metal Complexes: Limitations of Valence bond theory, Crystal field theory (CFT) splitting of d- orbitals in octahedral,tetrahedral and square planar complexes. Crystal Field Stabilization Energy (CFSE), Factors affecting 10Dq, Spectrochemical series, Effect of crystal field splitting on properties of Octahedral complexes, Magnetic Spectrals
17 Bio-inorganic Chemistry: Overview, essential and trace elements in biological processes, Metalloporphyrins with special referenceto haemoglobin and myoglobin. The role of Model systems, The alkali and alkaline earth metals,Metalloenzymes, Nitrogen fixation cycle.
18 Inorganic solid state chemistry: Introduction, Preparation of Nonmolecular solids, Band gaps, Metals, Insulators and Semi-conductors.Defects in Solids, Point defects: Schottky and Frenkel, Color center, extended defects. Nonstoichiometry
19 Organometallic Chemistry: (A) Definition, nomenclature and classification of organometallic compounds, EAN rule, 18 electron rule.General methods of preparations and properties. Structure and bonding in mononuclear metal carbonyls:Ni(CO)4, Fe(CO)5 and Cr(CO)6 (B) Polynuclear metal carbonyl: preparation and structures of Mn2(CO)10 , Fe2(CO)9and Fe3(CO)12(Orbital diagram not expected) (C) Sandwich compounds like Ferrocene: preparation, properties, reactions, structure and bonding. (D) Preparation and properties of alkyl and aryls of Li, Al, Hg and Ti.
20 Electronic spectra of Transition Metal Complexes: Introduction, Types of electronic transitions: The d-d transitions, Charge transfer transitions and Ligandligand transitions, Selection rules (Laporte Orbital and Spin), Applications (Ligand field strength, Colourof complexes, cis-trans isomerism and geometry of complexes).
21 Industrial fuels and chemicals: A) Industrial fuels like coal gas, producer gas and water gas. B) Physico chemical principles involved in the manufacture of HNO3(ostwald's method)and NH3 (Haber's Method)
22 Symmetry and Term symbols: Symmetry elements: Centre of symmetry, Rotation axis, Mirror plane, rotation reflection axis, Identity(Transdichloroethylene, H2O and BCl3).
23 Magnetic properties of transition metal complexes: Types of magnetic behaviour, Methods of determining magnetic susceptibility(Gouy's Method),Spin only formula, application of magnetic moment data for 3d metal complexes.
24 Selected topics: A) Nanochemistry: Introduction to nano particles, their properties and applications. B) Solid acids: Introduction to zeolites, structure and applications. C) Superconductors: Discovery, critical temperature, Meissner effect, Types: Conventional and HighTemperature superconductors.
25 Inorganic Polymers: Definition, Properties, Glass transition temperature, Classification (Condensation, addition andcoordination Polymers). Silicones: Preparation, structure & bonding and applications.
26 Thermodynamic and kinetic aspects of metal complexes: A brief outline of thermodynamic stability of metal complexes and factors affecting the stability,substitution reactions of octahedral complexes. Trans effect with respect to square planar complexes.
SR. No Physical Chemistry
1 Mathematical Concepts: Logarithmic relations, curve sketching, linear graphs and calculations of slopes differentiation offunctions,maxima & minima, partial, differentiation & reciprocity relations. Integration of someuseful/relevant functions
2 Gaseous State Postulates of kinetic theory of gase equation and derivation from ideal behavior, van der waal's equation of state. Critical phenomena; PV isotherms of van der waal's equation, relation between critical constants and ven der waal's constants, the law of corresponding states, reduced equation of state. Molecular Velocities: Root mean square, average and most probable velocities. Qualitative discussion maxwell distribution of molecular velocities, collision number, mean free path and collision diameter, liquifacation of gases (based on JouleThomson effect).
3 Chemical kinetics Rate of reaction, factors influencing the rate of a reaction concentration, temperature, pressure, solvent,light, catalyst Concentration dependence of rates mathematical characteristics of simple chemicalreaction. Zero order, first order, second order, pseudo order, half life & mean life. Determination of orderof reaction: Differential method Integration method, Method of half life period & Isolation method.Radioactive decay as a first order phenomenon. Theories of Chemical Kinetics. Effect of temperature onthe rate of reaction, Arrhenius equation and concept of activation energy. Simple collision theory basedon hard sphere model. Transition state theory (equilibrium hypothesis ). Expression for the rate constantbased on equilibrium constant & thermodynamic aspects.
4 Thermodynamics: Thermodynamic terms: System, surrounding, types of systems, intensive & extensive properties. State & path functions & their differentials. Thermodynamic process. Concept of work & heat First law ofthermodynamics : statements and definitions of internal energy & enthalpy. Heat capacities at constant volume and pressure and their relationship, joule's law joule-Thomson coefficient & inversion temperature .Calculation of w, q, dU, dH, for the expansion of ideal gases under isothermal & adiabatic conditions forreversible processes. Thermochemistry : standard state standard enthalpy of formation, Hess's law of heat summation & its applications. Heat of reaction at constant pressure & at constant volume . Enthalpy of neutralization, bond dissociation energy & its calculation from thermochemical data. Temperaturedependence of enthalpy kirchoff's equation
5 Solutions, Dilute Solutions and Colligative Properties: Ideal & non ideal solutions, methods of expressing concentrations of solutions, activity & activitycoefficients. Dilute properties Colligetive properties, Roult's law, Relative lowering of vapour pressure. molecular weight determination. Osmosis: osmotic pressure & its measurement, depression of freezingpoint, thermodynamic derivation of relation between molecular weight and depression of freezing point.Elevation in boiling point thermodynamic derivation of relation between molecular weight and elevationin boiling point. Experimental methods for determining various colligative properties.
6 Liquid State and Applications: Intermolecular forces, structure of liquids (Qualitative description) Structural differences between solids,liquids and gases. Liquid crystal : Difference between liquid crystals ,solid and liquid. Classification,structure of nematic and cholestric phases. Thermography and seven segment cell. Surface between aliquid and vapour .Surface tension by capillary rise method, stalagmometer method .Viscosity of liquids, poiseuilleequation, use of ostwald's viscometer,
7 Thermodynamics Second law of thermodynamics: need for the law, different statements of the law. Carnot cycle and itsefficiency, Carnot theorem. Thermodynamic scale of temperature. Concept of entropy :entropy as a statefunction ,entropy as a function of V & T, entropy as a function of P & T, entropy change in physicalchange, Clausius inequality ,entropy as a criteria of spontaneity and equilibrium .Entropy change in idealgases and mixing of gases. Third law of thermodynamics: Nernst heat theorem, statement and concept ofresidual entropy, evaluation of absolute entropy from heat capacity data. Gibbs and Helmholtz functions;Gibbs function (G) and Helmholtz function (A) as thermodynamic quantities, A & G as criteria forthermodynamic equilibrium and spontaneity, their advantages over entropy change. Variation of G and Awith P, V & T.
8 Chemical Equilibrium: Equilibrium constant and free energy thermodynamic derivation of law of mass action. leCheterlies's principle. Reaction isotherm and reaction isochore Clapeyron equaltion and Clausius Clapeyronequation, applications.
9 Phase Equilibrium: Statement and meaning of the terms phase , component and degree of freedom ,derivation of Gibbsphase rule, phase equilibria of one component system water,CO2 and S systems. Phase equilibria of twocomponent system solid liquid equlibria, simple eutectic Bi-Cd, Pb-Ag systems, desilverisation oflead. Solid solutions compound formation with congruent melting point (Mg-Zn) and incongruentmelting point, (NaCl-H2O), (FeCl3-H2O) and (CuSO4-H2O) system. Freezing mixtures, acetonedry ice.Liquids liquid mixtures mixture and Roule's and henry law. non- ideal liquid ideal system-azeotropes- HCl-H2O and ethanol water systems. Partially miscible liquids phenol water,trimethylamine water, nicotine water systems. Lower and upper consolute temperature. Effect ofimpurity on consolute temperature. Immiscible liquids, steam distillation. Nernest distribution lawthermodynamic derivation, applications.
10 Electrochemistry: Electrical transport conduction in metals and in electrolyte solutions, specific conductance andequivalent conductance measurement of equivalent conductance, variation of equivalent and specificconductance with dilution. Migration of ions and Kohlrausch law, Arrhenius theory of electrolytedissociation and its limitations, weak and strong electrolytes ,ostwald's dilution law its uses and limitations . Debye Huckel onsager's equation of strong electrolytes(elementary treatment only.)Transport number, definition and determination by Hittorf method and moving boundary method.Applications of conductivity measurements :determination of degree of dissociation, determination of kaof acids , determination of solubility product of a sparingly soluble salt, conductometric titrations.
11 Solid State: Defination of space lattice, unit cell. Laws of crystallography (i) law of constancy of interfacial angels(ii) law of rationality of indices (iii) law of symmetry elements in crystals. X-ray diffraction by crystals.Derivation of Bragg equation. Determination of crystal structure of NaCl, KCl and CsCl Laue's method and powder method).
12 Colloidal State: Definition of colloids, classification of colloids. Solids in liquids (sols): properties kinetic, optical andelectrical; stability of colloids, protective action, Hardy- schulze law gold number. Liquids in liquids(emulsions): types of emulsions, preparation .Emulsifier Liquids in solids (gels): classification,preparation and properties, inhibition, general applications of colloids.
13 Quantum Chemistry: De Broglie hypothesis and Heisenberg's uncertainty principle, sinusoidal wave equation, Hamiltonianoperator, Schrödinger wave equation and its importance, physical interpretation of the wave function, postulates of quantum mechanics, particle in one dimensional box. Schrödinger wave equation for Hatom, separation into three equations (without derivation), quantum numbers and their importance,hydrogen like wave function, radial wave functions, angular wave functions.
14 Electrochemistry: (A) Electrolytic and galvanic cells; reversible and irreversible cells, conventional representation ofelectrochemical cells; types of reversible electrodes; gas metal ion, metal-metal ion, metal-insoluble saltanion and redox electrodes, electrode reaction; Nernst equation; derivation of cell E.M.F. and singleelectrode potential, reference electrodes, standard hydrogen electrode; calomel electrodes; standardelectrodes potential, sign convention, electrochemical series and its applications. EMF of a cell and itsmeasurements; Concentration cells (both electrodes and electrolytes) with and without transport; liquidjunction potential and its measurement; Application of concentration cell; determination of ionic productof water; transport number of ions; solubility and solubility product. Polarization; elimination ofpolarization; decomposition potential, measurement of decomposition potential; factor affectingdecomposition potential over voltage and types of over voltage; measurement of over voltage ; factoraffecting over voltage. (B) Definition of pH, pOH pKa,and pKb; introduction to potentiometer; determination of pH usinghydrogen, quinhydrone and glass electrodes by potentiometric method; Buffer solution, types, bufferaction, buffer capacity ,mechanics of buffer action, Henderson-Hazelbulch equation. Corrosion-Types,theories - electrochemical and chemical. Energy sources: Acid and alkaline battery. Ni-Cd cell fuel cells,solar cells. Secondary batteries
15 Molecular Structure: Optical activity and molecular structure; polarization (Mosotti-Clausius equation), orientation of dipolesin an electric field, dipole moment, induced dipole moment, measurement of dipole moment; temperaturemethod and refractivity method, dipole moment and structure of molecules.
16 Nuclear Chemistry: Composition of the nucleus. Nuclear binding forces, binding energy, stability, nucleon-nucleon forces andtheir equality, characteristics and theory of nuclear forces. Nuclear models, the shell model, liquid dropmodel and its merits. Theory of radioactive disintegration, rate of disintegration half, average life of radioelement, units of radioactivity, definition and characteristics of artificial radioactivity. Determination andmeasurements of radioactivity: Ionisation current measurements; saturation collection; multiplicative ioncollection; the Geiger-Muller Counter, characteristics of an ideal Geiger-Muller Counter, proportional counter. methods based on photon collection, Scintillation counter, characteristics of a suitableScintillator. Nuclear fission, energy released in fission and fission products, neutron emission in fission,nuclear energy, classification of reactors, the breeder reactor, nuclear reactors in India.
17 Molecular structure and molecular spectra: Introduction to electromagnetic radiation; regions of the spectrum; statement of the Born-Oppenheimerapproximation; degrees of freedom. Rotational Spectrum: Diatomic molecules, energy level of a rigidrotor (semi-classical principles), selection rules, spectral intensity, distribution using populationdistribution (Maxewll-Boltzmann distribution); determination of bond length, qualitative description ofnon-rigid rotor, isotope effect.
18 Photochemistry: Interaction of radiation with matter, differences between thermal and photochemical processes, laws ofphotochemistry: Grothus- Drapper law, Stark-Einstein law, Jablonski diagram; depicting variousprocesses occurring in the excited state, quantum yield and its measurements qualitative description of fluorescence, phosphorescence, non-radiative processes (internal conversion, inter system crossing),photosensitized reactions-energy transfer processes (simple examples).
19 Spectroscopy: Vibrational Spectrum: Infrared spectrum: energy levels of simple harmonic oscillator, selection rules,pure vibrational spectrum, intensity, determination of force constant and qualitative relation of forceconstant and bond energies, effect of an- harmonic motion and isotope on the spectrum, idea ofvibrational frequencies of different functional groups. Raman spectrum: Concept of polarizability, purerotational and pure vibrational Raman spectra of diatomic molecules, selection rules.
SR. No Organic Chemistry
1 Structure and Bonding: Hybridization, C-C bond lengths and bond angles, bond energy, localized and delocalized chemicalbonds, Definition and examples of Van der Waals interactions, resonance, hyperconjugation, inductiveand field effects, intramolecular and intermolecular hydrogen bonding.
2 Fundamentals of Organic Chemistry: Curved arrow notation, drawing electron movement with arrows, half and double headed arrows,homolytic and heterolytic bond breaking. Types of reagents electrophiles and nucleophiles withexamples. Types of Organic Reactions: Addition, Elimination, Substitution, Oxidation, Reduction andRearrangement-one example of each. Energy profile diagrams for exothermic and endothermic reactions,single step and two step reactions. Reactive intermediates Carbocations, carbanions, free radicals,carbenes, arynes and nitrenes; examples, shape and ways of formation. Assigning formal charges onintermediates and other ionic species. Methods of determination of reaction mechanisms (one exampleeach of product analysis, intermediates, isotope effects, kinetic and stereochemical studies). Theory ofacids and bases: Lewis concept; Bronsted and Lowry concept.
3 Alkanes and cycloalkanes: IUPAC nomenclature of alkanes. General methods of formation (with special reference to Wurtz reaction,Kolbe reaction, Corey-House reaction & decarboxylation of carboxylic acids). Physical properties andchemical reactions of alkanes: halogenation, combustion and pyrolysis. Mechanism of free radicalhalogenation of alkanes: orientation, reactivity and selectivity with propane as an example. Cycloalkanesnomenclature, general methods of formation, Baeyer strain theory and its limitations. Ring strain insmall rings (cyclopropane and cyclobutane), theory of strainless rings. The case of cyclopropane ring:banana bonds.
4 Alkenes, dienes and alkynes: IUPAC nomenclature of alkenes, general methods of formation, mechanisms of dehydration of alcoholsand dehydrohalogenation of alkyl halides, regioselectivity in alcohol dehydration. The Saytzeff rule,Hoffmann elimination, physical properties and relative stabilities of alkenes. Chemical reactions ofalkenes Epoxidation, ozonolysis, hydration, hydroxylation and oxidation with KMnO4. Mechanismsinvolved in hydrogenation, electrophilic and free radical additions, Markownokoff's Hydroboration-oxidation, oxymercuration-reduction. Polymerization of alkenes. Substitution at the allylic and vinylicpositions of alkenes. Industrial applications of ethene and propene. Nomenclature and classification ofdienes, isolated, conjugated and cumulated dienes. Structure and stereochemistry of allenes, methods offormation of butadiene, polymerization. Chemical reactions 1,2- and 1,4-additions, Diels-Alderreaction. Nomenclature, structure and bonding in alkynes. General methods of formation. Chemicalreactions of alkynes, acidity of alkynes. Mechanism of electrophilic and nucleophilic addition reactions,metal-ammonia reduction and polymerization
5 Stereochemistry of organic compounds: Newman and saw horse formulae, Fischer and flying wedge formulae. Concept of isomerism. Types ofisomerism. Conformational isomerism Conformational analysis of ethane and nbutane; conformationsof cyclohexane, axial and equatorial bonds, conformation of monosubstituted cyclohexane derivatives.Optical isomerism elements of symmetry, molecular chirality, definition and examples of enantiomers,stereogenic centre, optical activity, properties of enantiomers, chiral and achiral molecules with twostereogenic centers, diastereomers, threo and erythro diastereomers, meso compounds, resolution ofenantiomers, inversion, retention and racemization. Specification of configuration at chiral centers:Sequence rules and R:S system of nomenclature. Geometric Isomerism - Determination of configurationof geometric isomers. E and Z system of nomenclature, geometric isomerism in oximes and alicycliccompounds. Difference between configuration and conformation
6 Arenes and Aromaticity: Nomenclature of benzene derivatives. Structure of benzene: molecular formula and Kekule structure.Stability and C C bond lengths of benzene, resonance structure, MO picture. Aromaticity The Huckel's rule, aromatic ions, anti-aromaticity. Aromatic electrophilic substitution general pattern of the- Mechanism Role of absilon and pie- complexes. Mechanism of nitration, halogenation, sulphonation and FriedelCrafts reaction. Activating and deactivating substituents, orientation and ortho/para ratio. Side chainreactions of benzene derivatives. Birch reduction. General methods of formation and chemical reactionsof alkyl benzenes reduction, oxidation, ring and side chain substitution
7 Alkyl and aryl halides: Nomenclature and classes of alkyl halides, general methods of formation, chemical reactions. Mechanismand stereochemistry of nucleophilic substitution reactions of alkyl halides, SN2 and SN1reactions withenergy profile diagrams, solvent effect. The addition elimination (bimolecular displacement) and theelimination addition (benzyne) mechanisms of nucleophilic aromatic substitution reactions. Relativereactivities of alkyl halides vs. allyl, vinyl and aryl halides.
8 Electromagnetic Spectrum: Absorption Spectra: Ultraviolet (UV) absorption spectroscopy Absorption laws (Beer-Lambert law), Molar absorptivity,presentation and analysis of UV spectra, Types of electronic transitions, effect of conjugation. Concept ofchromophore and auxochromes, Bathochromic, hypsochromic, hyperchromic and hypochromic shifts.UV spectra of conjugated dienes and enones, Woodward-Fieser rules for calculation of UV maxima of theabove two systems. Numerical problems on above. Infra Red (IR) absorption spectroscopy Molecular vibrations, Hooke's law, Selection Rule,Intensity and position of IR bands, measurement of IR spectrum,Finger print region and its use to establish identity, Applications to determine purity, to study progress ofchemical reactions and hydrogen bonding. Characteristic absorptions of various functional groups andinterpretation of IR spectra of simple organic compounds. Simple problems in structure elucidation usingUV and IR spectroscopy.
9 Alcohols: Classification and nomenclature. Monohydric alcohols Methods of preparations by reduction ofcarbonyl compounds, carboxylic acids, and esters, using Grignard reaction. Hydrogen bonding, acidicnature. Reactions of alcohols esterification, oxidation and dehydration. Dihydric alcoholsNomenclature, methods of preparation by hydroxylation of alkenes and acid catalyzed opening ofepoxides. Reactions of vicinal glycols pinacol-pinacolone rearrangement with mechanism.
10 Ethers and Epoxides: Nomenclature of ethers and methods of preparation by Williamson synthesis, from alcohols by use ofdiazomethane and by use of H2SO4. Physical properties. Chemical reactions: cleavage with HI. Synthesisof epoxides by reaction of alkenes with peracids and by elimination from vicinal halohydrins. Acid and base catalyzed ring opening of epoxides, orientation of ring opening, reactions of Grignard andorganolithium reagents with epoxides.
11 Aldehydes and Ketones: Nomenclature and structure of the carbonyl group. Synthesis of aldehydes by oxidation of alcohols andreduction of acid chlorides, synthesis of ketones by oxidation of alcohols, from nitriles by Grignardreaction and from carboxylic acids. Physical properties. Mechanism of nucleophilic additions to carbonylgroup with particular emphasis on benzoin, aldol, Perkin and Knovenagel condensations, reaction withammonia and its derivatives, Wittig reaction and Mannich reaction. Halogenation of enolizable ketones. Mechanisms and one application each of the above reactions.
12 Phenols: Nomenclature, structure and bonding. Preparation of phenols by alkali fusion of aromatic sulphonic acids, Dow's process from chlorobenzene and from cumene through, hydroperoxide rearrangement withmechanism. Physical properties and acidic character. Comparative acid strengths of alcohols and phenols,resonance stabilization of the phenoxide ion. Reaction of phenols Electrophilic aromatic substitution,acylation and carboxylation. Mechanisms of Fries rearrangement, Claisen rearrangement, Gattermannsynthesis and Riemer-Tiemann reaction.
13 Oxidation and Reduction reactions of carbonyl compounds: Oxidation of aldehydes, Baeyer-Villiger oxidation of ketones, Cannizzaro reaction, Meerwein-PondorfVerley, Clemmensen, Wolff-Kischner, LiAlH4 and NaBH4 reduction. Mechanisms and one applicationeach of the above reactions
14 Carboxylic Acids: Nomenclature, structure and bonding. Physical properties, acidity and effects of substituents on acidstrength. Preparation of carboxylic acids by oxidation of carbonyl compounds, carbonation of Grignardreagent, hydrolysis of cyanides, preparation of aromatic acids by oxidation of alkyl benzenes. Reactionsof carboxylic acids. Hell-Volhard-Zelinsky reaction, synthesis of acid chlorides, esters and amides.Reduction of carboxylic acids. Mechanism of decarboxylation. Dicarboxylic acids: Methods ofpreparation and effect of heat and dehydrating agents with reference to malonic acid only
15 Carboxylic Acids Derivatives Structure and nomenclature of acid chlorides, esters, amides and acid anhydrides. Physical properties.Methods of preparation from carboxylic acids and interconversion of acid derivatives by nucleophilic acylsubstitution. Mechanisms of esterification and acidic and basic hydrolysis of esters with evidences.
16 Organic Compounds of Nitrogen Preparation of nitroalkanes and nitroarenes. Chemical reactions of nitroalkanes. Mechanisms ofnucleophilic substitution in nitroarenes and their reductions in acidic, neutral and alkaline media. Picricacid preparation and properties. Structure and nomenclature of amines, physical properties.Stereochemistry of amines. Separation of a mixture of primary, secondary and tertiary amines. Structuralfeatures affecting basicity of amine. Amine salts as phase-transfer catalysts. Preparation of alkyl and arylamines by reduction of nitro compounds and nitriles, reductive amination of carbonyl compounds,Gabriel phthalimide reaction and Hofmann bromamide reaction.
17 Spectroscopy: Proton Magnetic Resonance (1H NMR) spectroscopy, theory, nuclear shielding and deshielding, chemicalshift and molecular structure, spin-spin splitting and coupling constants, intensity of peaks, interpretationof PMR spectra of simple organic molecules. 13C Magnetic Resonance: Number of signals, splitting ofsignals proton coupled and decoupled spectra, off resonance decoupled spectra. 13CMR chemical shifts identification of hybridization of carbons and nature of functionalization. Mass Spectrometry: Simpleidea of instrumentation, Definitions of parent or molecular ion peak and base peak. Isotope effect withrespect to alkyl halides, Fragmentation of ketones Alpha Cleavage and MC lafferty rearrangement.Problems pertaining to the structure elucidation of simple organic molecules using spectroscopic techniques (UV,IR, PMR, CMR and MS). Types of problems to be specified. UV and IR to be used as supporting data.Types of CMR and Mass spectroscopy problems to be specified.
18 Alkaloids: Structure elucidation and synthesis of Nicotine, Atropine and Papaverine.
19 Stereochemistry of Reactions: Mechanism and stereochemistry of (i) Addition of halogens and halogen acids to open chain alkenes.Markownnikoff's and anti- Marownnikoff's addition. ii)SN1, SN2, SNi , substitutions and (iii) E1, E2andE1cb elimination reactions.
20 Heterocyclic Compounds: Introduction, Molecular orbital picture and aromatic characteristics of pyrrole, furan, thiophene andpyridine. Methods of synthesis and chemical reactions with particular emphasis on the mechanism ofelectrophilic substitution. Mechanism of nucleophilic substitution reactions in pyridine derivatives.Comparison of basicity of pyridine, piperidine and pyrrole. Introduction to condensed 5 and 6 memberedheterocycles. Preparation and reactions of indole, quinoline and isoquinoline with special reference toFischer indole synthesis, Skraup synthesis and Bischler-Napieralski synthesis. Mechanism of electrophilicsubstitution reactions of indole, quinoline and isoquinoline.
21 Vitamins and Hormones: Vitamins: Importance and classification. Structure elucidation and synthesis of Vitamins A and C.Hormones: Important hormones and their uses. Structure elucidation and synthesis of Thyroxine andAdrenaline.
22 Amino acids, Peptides, Proteins and Nucleic Acids: Classification, structure and stereochemistry of amino acids. Acid-base behavior, isoelectric point and electrophoresis, preparation and reactions of alpha-amino acids.Structure and nomenclature of peptides andproteins. Classification of proteins. Peptide structure determination, end group analysis, selectivehydrolysis of peptides. Classical methods of peptide synthesis, solid-phase peptide synthesis. Structuresof peptides and proteins. Levels of protein structures. Protein denaturation/renaturation. Nucleic acids:Introduction. Hydrolysis of nucleic acids. Ribonucleosides and ribonucleotides. General idea of thedouble helical structure of DNA glucose. Mechanism of mutarotation. Formation of glycosides, ethersand esters. Structure elucidation of sucrose.
23 Terpenes: Classification. General methods of structure elucidation. Chemistry and synthesis of citral and its Conversion to ionones, chemistry and synthesis of alpha-terpineoil camphor, terpiniol camphor, chemistry of alpha- -pinene.Chemistry of zingiberene.
24 Organic synthesis via Enolates: Acidity of Alpha-hydrogens, Synthesis of ethyl acetoacetate by Claisen condensation, keto-enol tautomerismin ethyl acetoacetate. Alkylation of diethyl malonate and ethyl acetoacetate. Alkylation of 1,3-dithianes. Alkylation and acylation of enamines.
25 Fats, Oils and Detergents: Natural fats, edible and industrial oils of vegetable origin, common fatty acids, glycerides. Hydrogenationof unsaturated oils. Saponification value, iodine value and acid value of oils. Soaps, synthetic detergents,alkyl and aryl sulphonates.
26 Synthetic Polymers: Addition or chain-growth polymerization. Free radical vinyl polymerization, ionic vinyl polymerization, Zeigler-Natta polymerization and vinyl polymers. Condensation or step-growth polymerization.Polyesters, polyamides, phenol-formaldehyde resins, urea-formaldehyde resins, epoxy resins andpolyurethanes. Natural and synthetic rubbers.
27 Photochemistry: General idea of photochemical reactions. Electronic transitions and transition states. Jablonskii diagram. Norrish type I and Norrish type II cleavage of ketones.